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Evert AB, Boucher JL, Cypress M, Dunbar SA, Franz MJ, Mayer-Davis EJ, et al

Indeed, targeting FADS1/2 renders the aggressive TNBC cells resistant to ferroptosis as the addition of exogenous MUFA to the aggressive models exerts an anti-ferroptosis effect and prevents the detrimental effects of lipid peroxidation, whereas increasing the availability of PUFA resensitizes the resilient models to ferroptosis execution

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