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Cloning the GLP-1 receptor Another important chapter was opened up for understanding the biology of GLP-1 by the cloning of the GLP-1 receptor

The largest of these (still fairly small, n=159) was a randomized and controlled clinical trial published in the New England Journal of Medicine , and found that a dose of 100 mcg twice per day improved quality of life, reduced eye involvement, and slowed disease progression among participants with mild Graves' orbitopathy (compared to pentoxifylline or placebo)

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But it has completed phase 3 studies showing it helps diabetes patients reduce their sugar levels