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The dual GIP/GLP-1 mechanism of tirzepatide appears to provide superior efficacy

Tirzepatide's dual GIP/GLP-1 mechanism is particularly effective for PCOS because it directly improves insulin resistance

People with oral lesions, chronic dry mouth, or conditions affecting the sublingual mucosa

Most people begin losing weight on semaglutide within 24 weeks, with more noticeable and consistent weight loss typically occurring after 812 weeks, once doses are increased to therapeutic levels

Higher doses may correlate with a more significant risk of nausea, vomiting, and gastroparesis

However, when the experiments were done with GLP-1, blood glucose was reduced [22]