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6) Pregnancy Sex hormones during pregnancy increase FMO3 enzyme activity, which can increase TMAO [54]

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A more comprehensive approach would be to concurrently measure actual protein levels (e.g., WB, ELISA, etc.) of potential targets in addition to inhibitor assays

Nevertheless, systemic cytokine inhibition poses risks, primarily by weakening host defenses, which is a considerable limitation (102)

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