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[127] [128] Synthesis [edit] Biosynthesis [edit] Vitamin B 12 is derived from a tetrapyrrolic structural framework created by the enzymes deaminase and cosynthetase which transform aminolevulinic acid via porphobilinogen and hydroxymethylbilane to uroporphyrinogen III

There are so many reasons why a supplement might not work for you, and this is where understanding your body and underlying drivers helps to find what works for you

Vitamin B12 shots are recommended for people who cannot absorb enough through food or oral supplements

Your doctor can prescribe testosterone therapy as part of gender-affirming treatment

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