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Similar to REMODEL, the SMART trial (NCT04889183), completed in 2024, explored mechanisms of human kidney protection by 2.4 mg subcutaneous semaglutide in 125 overweight/obese participants with A2A3 albuminuria without T2DM, with a primary endpoint of albuminuria

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Moreover, Semaglutide GLP-1 and Liraglutide have been shown to have beneficial effects on cardiovascular risk factors

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Some experts say that analgesics like aspirin and acetaminophen can strain the liver when metabolized