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Elevated IGF-1 levels raise concerns about potential proliferative effects on existing malignancies, making growth hormone therapy problematic for individuals with cancer history or elevated cancer risk

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Researchers continue investigating how NNMT-related mechanisms may affect obesity, glucose metabolism, and energy expenditure

For instance, high levels of UPF consumption have been found to be associated with an increased odds of developing ASD in adolescents, while experimental studies indicate that acrylamide, which is a compound frequently present in UPFs, may, in some cases, induce autism-like behaviors as a result of a number of important pathophysiological mechanisms that result in neuroinflammatory changes as well as oxidative stress (151, 160)

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