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This likely represents an adaptive response to Mtb infection, optimising lysine use for NADH and FADH generation through the oxidation of glutaryl-CoA, despite consuming -ketoglutarate, a TCA cycle intermediate (Leandro & Houten, 2020
Higher doses or repeat treatments should only be given on a veterinarians recommendation
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SAM Inhibiting NNMT is reported to raise cellular NAD+ and SAM
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