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GLP-1 receptor agonists like retatrutide reduce Cyp2e1 expression by 40-60%, slowing alcohol metabolism and causing higher blood alcohol concentrations to persist longer

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How the oxidant/antioxidant balance could modulate genomic DNA replication inside parasite nucleus remains to be understood in future studies

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Finally, the ability of GLP-1(2836) to decrease cleaved caspase-3 activation suggests that the agent prevents apoptosis (Figure 3E)