Given their popularity and the results that are being seen with their use, that is a question that is unlikely to get answered in a satisfactory way anytime soon and should be left to the individual and their prescribing physician.
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Starting at just $129 monthly, this protocol uses lower initial doses to assess individual tolerance and metabolic response before dose optimization
Results outside this range suggest quality control problems
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However, if it is almost time for the next dose, skip the missed dose and go back to the regular dosing schedule