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Peptide YY, release from small intestine in response to meals, signals satiety and reducing gastric motility, which slows down the emptying of the stomach
For weight management, reduced dosing frequency may diminish the appetite-suppressing effects and lead to weight regain
indeed, if some studies showed that the hormone is able to significantly downregulate autophagy in different disease models 63,64,65 , other reports failed to confirm those findings, providing evidence for an enhancement of the autophagic process upon melatonin treatment 66,67,68
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