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The following antibodies were used for immunohistochemistry: anti-GPX4 (1:400, Abcam, ab125066), anti-4HNE (1:400, Abcam, ab46545) and anti-MPO (1:200, Dako, IS511) were employed with a secondary biotinylated antibody (Vector, MP-7401)

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compounding regulations

i.e., markers of excitatory neurons), and a decrease in the expression of GAD65 and gephyrin (i.e., markers of inhibitory neurons) (111), suggesting a net result of excitatory-dominant E/I imbalance