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Weight loss injections, particularly glucagon-like peptide-1 (GLP-1) receptor agonists such as semaglutide (Wegovy for weight management, Ozempic for type 2 diabetes) and tirzepatide (a dual GIP/GLP-1 receptor agonist marketed as Zepbound for weight management and Mounjaro for type 2 diabetes), have become increasingly prescribed medications

The injection also reversed the feminization expression pattern of CYP2B9, CYP2D9, CYP4A12, CYP7B1, ELOVL3 (dominant expression genes in female mice) in the liver to that of wild-type male mice

Diabet Obes Metab 20:6068

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