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10.1016/S1474-4422(17)30470-2 434 ThompsonR

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And minocycline and doxycycline can block Fe 2+ uptake into the matrix through the Ca 2+ /Fe 2+ uniporter, also limiting MPT formation in murine models

This suggests that under T2 stressed conditions, increases in SLC7A11 activity help maintain intracellular redox balance (Figure 3G)