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Similarly, Nestor et al

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Further, higher baseline BMI and A1C may suggest that lower income individuals wait longer to add second line therapies, like GLP-1 RAs, potentially due to the high cost relative to first line therapies (such as metformin)

Risk of cardiovascular outcomes in patients with type 2 diabetes after addition of SGLT2 inhibitors versus sulfonylureas to baseline GLP-1RA Therapy

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FDA also found no nonclinical study assessing behavioural or electroencephalographic sleep endpoints following Epitalon exposure