Compounds such as EGCG and apigenin promote apoptosis in melanoma cells by modulating pathways like MAPK and PI3K-AKT, while green tea polyphenols inhibit histone deacetylase (HDAC) and activate histone acetyltransferase (HAT), reactivating tumor-suppressor genes silenced during melanoma progression 138,148
Supporting normal detoxification pathways
In contrast to the liver toxicity of acetaminophen, NSAIDs exhibit varying degrees of gastrointestinal, cardiovascular, and kidney toxicity
Consensus statement on essential patient characteristics in systemic treatment trials for metastatic colorectal cancer: Supported by the ARCAD Group
These well-known ingredients work together to promote antioxidant protection, support immune function, and help maintain your bodys natural ability to take care of your skin from within.*
Assali, Georgia Colleluori, Saverio Cinti, Alexandra J