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Side effects, particularly nausea, vomiting and digestive discomfort, are significantly more likely and more intense when doses increase faster than the body can adjust

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Biol Direct 10, 73, doi: 10.1186/s1306201501034 (2015)

Understanding your genetic predispositions can help frame a more informed discussion with your provider about whether the additive benefit of combination therapy addresses your specific metabolic phenotype, or whether monotherapy or alternative agents might be more efficient for your genetics and lifestyle

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