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Boonyuen, U

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Pharmacological activation of the System Xc-/GSH/GPX4 axis has emerged as a promising avenue for the management of ferroptosis-related ocular diseases, as it can suppress ferroptosis by replenishing GSH precursors, upregulating the expression or activity of SLC7A11, or directly stabilizing GPX4 protein to resist its inactivation (132)

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