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Retrospective review revealed that his fibrosis-4 (FIB-4) score had exceeded high-risk thresholds before GLP-1 therapy initiation, yet no fibrosis risk stratification had been performed

So I think anybody can get Alzheimer's disease with any genotype if there's enough insulin resistance, if there's basically enough difficulty in getting glucose through pyruvate dehydrogenase and into the Krebs cycle

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Nigrescent: Growing darker