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Further studies with increased sample size and efforts to identify the metabolite markers by a more sensitive complementary method such as mass spectrometry can be used to further corroborate these findings

Underlying mechanisms may involve microbial-mediated drug metabolism, transformation, and modulation of intestinal barrier function

By directly increasing circulating glutathione, IV therapy supports the continuous neutralization of free radicals and protects cells from oxidative stress

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Cancer-associated IDH1 promotes growth and resistance to targeted therapies in the absence of mutation

(1) Vitamin B12 offers further cellular protection by supporting telomere maintenance, the protective caps at the ends of chromosomes