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The omega-3 fatty acids docosahexaenoic acid and eicosapentaenoic acid serve a role in reducing the resistance of tumor cells to bortezomib by activating the serine synthesis pathway, mitochondrial folate cycle, methionine cycle-associated GSH synthesis and ChaC1-mediated GSH degradation in tumor cells, ultimately promoting GSH degradation (138)
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Materials and methods Drugs Levothyroxine sodium hydrate (LT4) (powder form, pack size: 50 mg, Sigma-Aldrich, MO, USA) and dapagliflozin (DAPA) (5 mg film-coated tablet, AstraZeneca Pharmaceuticals LP, Indiana, USA) were used in this study
Needle insertion: Insert needle at 4590 angle into the pinched skin fold (45 for thin individuals
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