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Flushing occurs in 1015% of patients and is caused by rapid histamine release as glutathione enters circulation

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J Investig Allergol Clin Immunol 28(2):132134 Reinhart JM, Rose W, Panyard DJ, Newton MA, Liebenstein TK, Yee J, Trepanier LA (2018) RNA expression profiling in sulfamethoxazole-treated patients with a range of in vitro lymphocyte cytotoxicity phenotypes

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Further small-scale clinical trials are needed to validate GSHs therapeutic effects in patients with TB