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The FDA has specifically flagged risks with unapproved GLP-1 products and has reported dosing errors and hospitalizations associated with compounded injectable semaglutide

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For those interested in even more significant weight loss, compounded tirzepatide at $349 per month offers another option with higher average weight loss in clinical trials

However, feeling cold is not a direct side effect of Wegovy or other semaglutide drugs

Clinical trials have demonstrated semaglutide effectiveness for weight management, with an average of 15 percent body weight lost after 52 weeks of treatment in obese and overweight patients who had no history of diabetes, hypertension or cardiovascular disease