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hormonal changes, slowed metabolism, stress, genetics, or lifestyle habits

The goal is the lowest dose that keeps you at your target weight with manageable side effects

Ling NXY, Langendorf CG, Hoque A, Galic S, Loh K, Kemp BE, et al

De Angelis M, Mascellino MT, Miele MC, et al

The pivotal clinical trials for Wegovy, including the STEP programme (Semaglutide Treatment Effect in People with obesity), involved thousands of participants followed for up to 68 weeks

I only really hear about microdosing when it comes to compounding medications, which we never recommend, or off-label use of GLP-1s for longevity, addiction, and other indications. Although many doctors are writing prescriptions for GLP-1 microdosing, experts are concerned that they may not always be acting scrupulously, especially when working with less-reputable online compounding pharmacies