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Amylin, a neuroendocrine hormone co-released with insulin, controls hunger, gastric motility, glucagon secretion, and energy metabolism via divergent amylin receptor (AMYR) subtypes (1-3), namely the calcitonin receptor (CTR) and the receptor activity-modifying proteins (RAMPs)

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Our goal is to select compounds with moderate metabolism to ensure effective therapeutic efficacy

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Central nervous system effects have been reported occasionally, including headaches, dizziness, insomnia, and irritability

Who should be especially cautious before combining semaglutide with blood pressure medication