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Furthermore, many medications induce ferroptosis, particularly with compounds like Dihydroartemisinin and Brusatol

doi: 10.1016/0014-5793(96)00272-4

Upon exposure to H 2 O 2 , the free iron in lysosomes increases the production of ROS, which can then be released through an unstable lysosomal membrane to trigger the activation of cell death pathways 12

Increased oxidant-induced apoptosis in cultured nondividing human retinal pigment epithelial cells

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Organophosphorus pesticides (OPs) are common neurotoxic substances