Transl Psychiatr 2021;11:23
GLP-1 receptor agonists and GLP-1 and glucose-dependent insulinotropic peptide agonists have several mechanisms of action, including reduction of gastric emptying, inhibition of glucagon secretion, beneficial changes in the intestinal microbiome, and direct effects on hypothalamic nuclei to enhance satiety (which promotes weight loss)
Fat emulsion tolerance in preterm infants of different gestational ages in the early stage after birth
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Severe Hypoglycemia Coadministration of SYMLIN with mealtime insulin increases the risk of severe hypoglycemia, particularly in patients with type 1 diabetes [see Boxed Warning and Warnings and Precautions (5.1)]
emphasized that the interplay between HPA axis hyperactivity and neuroinflammation is crucial in the etiopathogenesis of MDD, suggesting that targeting these pathways may enhance the efficacy of antidepressant treatments [81]