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Discussion While the overall number of GLP-1 RA exposures increased during the study period, outcomes were largely benign, with the most common being no effect

Duration : Treatment can take 1 to 2 hours

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Weight loss in the first week is generally minimal and should not be used as a primary indicator of treatment success

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Ipamorelin's human data is limited to two published pharmacokinetic/pharmacodynamic studies: a 1999 PK/PD study (PMID: 10496658) that documented dose-response relationships and peak GH at 30-40 minutes post-injection in human volunteers, and a completed Phase II clinical trial for postoperative ileus (NCT00672074), after which ipamorelin's development for this indication was discontinued without approval