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At three to seven injections per week, they compound

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Two independent reviewers performed the study selection process and any disagreements were resolved by a third reviewer

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This is somewhat higher than the 30% rate seen with semaglutide, likely because tirzepatide activates both GIP and GLP-1 receptors, creating stronger effects on gut function

Skipping this consideration could increase the risk of compounded side effects such as nausea, vomiting, diarrhea, or hypoglycemia when combined with other diabetes medications