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For example, luteolin (a flavonoid from Chrysanthemum and others) decreased infarct size and improved cardiac function in rat I/R models via Nrf2 activation and HO-1 upregulation (Oyagbemi et al., 2018)

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After 48 h, the mice were sacrificed, and the tumors as well as major organs (heart, liver, spleen, lung, kidney) were collected to measure their fluorescence intensity