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Hydrate Flush out metabolites and reduce sulphite load

When consuming the same amount of folic acid, people with the MTHFR 677 TT genotype (two copies of T, one copy from each parent) have on average 16% less folate in their blood than people with the MTHFR 677 CC genotype (two copies of C)

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17(12): CR677CR682.

This confirms that the observed metabolic reprogramming was dependent on chronic activation of GLP-1R signalling and independent of its acute stimulation of insulin secretion, which may result in autocrine insulin signalling

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