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64 , e2000231 (2020)

[55] Cellular aging and autophagy [edit] Pathological aging and metabolic diseases are often characterized by defective mitochondria, the accumulation of misfolded proteins, and cellular senescence

Consequently, oxidative stress and inflammation interact to promote the development of neurodegenerative diseases

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"If it hits 40% of the people, at the end of the day, if this becomes something that is as widely accessible as conversations [about it suggest], it should have a very large impact," he said