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One year after diet-induced weight loss of about 13.5 kg, leptin remained 35% below baseline

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More data on the efficacy and safety of the existing or potent anti-diabetic drugs for T2DM in PWS are in urgent need since lifestyle interventions are difficult to achieve in all PWS patients especially during adolescence

Taraxasterol ameliorates bone loss of ovariectomized mice via suppressing the NLRP3 inflammasome and modulating the gut microbiota