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A pilot randomized clinical trial (RCT) testing PD patients to maintain a low-fat or ketogenic diet for 8 weeks observed that both groups significantly improved in motor and nonmotor symptoms, but the ketogenic group showed greater improvements in nonmotor symptoms (Phillips et al., 2018)

For example, tirzepatidea dual GLP-1/GIP agonist already approved for adult obesityis being evaluated in adolescents with obesity

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This difference indicates that the addition of icodec displaces or prevents the binding of semaglutide to albumin

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doi: 10.1016/j.ymben.2018.04.008 49 AuldFMaschauerELMorrisonISkeneDJRihaRL