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NMN treatment led to the upregulation of genes associated with energyrelated metabolic pathways such as oxidative phosphorylation, pyruvate metabolism, fatty acid metabolism, GSH metabolism, glycolysis/gluconeogenesis, fatty acid degradation, and valine, leucine, and isoleucine degradation in the ovaries of the mice in the aged group (Figure 5F), indicating an increase in energyrelated metabolic processes such as amino acid metabolism, lipid metabolism, and oxidative phosphorylation in aged mouse ovarian tissues following NMN treatment

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