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The injected hydroxocobalamin is transported via the bloodstream to tissues throughout the body, where it acts as a cofactor for two critical enzymatic reactions: the conversion of homocysteine to methionine and the conversion of methylmalonyl-CoA to succinyl-CoA

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The preclinical research is extensive for a peptide: VEGF upregulation, nitric oxide signaling effects, gastric ulcer healing in animal models, intestinal anastomosis healing (Sikiric et al., Current Pharmaceutical Design, 2014)

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