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doi: 10.1186/S12917-016-0676-X 31 GallerAISuchodolskiJSSteinerJMSungCHHittmairKMRichterBet al

Upon activation, mast cells rapidly release pruritogenic mediators such as histamine, prostaglandin D 2 (PGD 2 ), tryptase, and -hexosaminidase (Poto et al., 2022), which collectively stimulate C-type sensory nerve fibers and trigger neuroimmune amplification (Siiskonen and Harvima, 2019)

doi: 10.1016/j.amjcard.2018.02.030 29 IdaSKanekoRImatakaKOkuboKShirakuraYAzumaKet al

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However, GB demonstrated immunosuppressive effects at high dietary levels (4 g GB/kg intake), indicating that its levels in the diet should be optimized [100]

Po wyprodukowaniu i uyciu jest rozkadany przez enzym zwany gamma-glutamylotransferaz (GGTP)