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A recent study has found that 25 Hz repetitive transcranial magnetic stimulation alleviates glutamate excitotoxicity and upregulates the expression of glutamate transporter-1 (GLT-1) by activating phosphatidylinositol-3-kinase (PI3K)/protein kinase B (AKT) in 3xTg AD mice [10]

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doi: 10.3390/ijerph18031105

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Blood Collection and Biochemical Analysis At the end of the treatment period (21 days), blood samples (7ml) was obtained from the retro-orbital sinus of each animal under mild ether anaesthesia into a heparinised EDTA tubes to prevent coagulation