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Frontiers in pharmacology , 12 , 627533

We also note that this accommodates potential for collective improvementif hospitals with at least three Safety of Care measures improve in performance relative to those with one or two, then fewer than 25 percent of those with at least three measures would find themselves in that lowest overall quartile

This review synthesizes current evidence regarding SGLT2 inhibitors and GLP-1 receptor agonists in DKD, examines their mechanisms and clinical outcomes, and highlights future research directions to address ongoing therapeutic needs

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Pharmacological treatment is considered as an adjunct, not a replacement, for these fundamental interventions