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The dopamine metabolic pathway mediated by MAO-B can generate hydrogen peroxide (H 2 O 2 ), and with the increase of MAO-B activity, excessive H 2 O 2 leads to oxidative stress and neuronal damage (Jiang et al., 2015a)

Vesicular Displacement : Within the vesicle, ephedrine competes with and displaces stored norepinephrine into the neuronal cytoplasm (Alex Yartsev, 2025

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However, other studies have indicated that GLP-1RAs are linked to a reduced risk of lung cancer, independent of smoking status [19]

72 Thus, investigation in patient responders of the efficacy of flupirtine, or related drugs exhibiting a similar pharmacology, as a treatment approach would be of interest

Scully for his assistance with the GRID analysis