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showed that DCA inhibits pyruvate dehydrogenase kinase in glioblastoma, shifting metabolism from glycolysis to mitochondrial oxidative phosphorylation

doi: 10.1111/j.1464-5491.1990.tb01375.x

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Instead, our findings demonstrate an important role for GSH in the liver, where under resting conditions, GSH maintains low NRF2 activity to permit ample expression of lipogenic enzymes, promotes the production of triglycerides, and sustains lipid abundance in vivo

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28 , e12649 (2019)