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As postprandial hyperglycemia was observed in intestinal epithelial cell-specific Sirt1 KO mice, SIRTs could be the molecule connecting intestinal NAMPT-mediated NAD + biosynthesis and canonical Wnt signaling to stimulate GLP-1 secretion [31,94] (Figure 2 and Figure 3)

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Thus, in the context of moldy environments, IL13 variants do not change how mycotoxins are detoxified, but they change how vigorously the immune system responds in the airways

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