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Semaglutide and Diverticulitis: Safety Considerations for Patients Taking semaglutide with diverticulitis is not automatically contraindicated, but it requires clear communication between you, your gastroenterologist, and your weight loss provider

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Your provider should evaluate contraindications and precautions, including personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2, which are absolute contraindications to GLP-1 receptor agonists

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When resuming after a dose hold, drop back to the previous dose level and maintain that level for an additional 4 weeks before attempting escalation again