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This topic has gained much recent interest, and initial studies evaluating a possible effect of the bacteria in our gut are ongoing

Preclinical evaluation of the CDK4/6 inhibitor palbociclib in combination with a PI3K or MEK inhibitor in colorectal cancer

10.6026/97320630011182 [DOI] [PMC free article] [PubMed] [Google Scholar] Baune, M.C

doi:10.1007/s42399-025-01814-6

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The therapeutic limitations of the use of sulforaphane in cancer are represented by the complete lack of knowledge of the potential anticancer effects at the cellular level and the effects on the immune system, the lack of translational studies to establish the effective doses in humans, and the interactions with conventional chemotherapy medication