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In the TME of chronic hypoxia and nutritional deficiency, exosomes secreted by CAF carry significant lactate, acetate, and amino acids to promote tumour metabolism, including PPP, glutamine decomposition, and nucleotide metabolism

If you are taking berberine or other glucose-management supplements alongside your GLP-1 medication, monitor blood sugar carefully when introducing fiber supplements, as the combined effect could cause hypoglycemia

Beyond weight loss, tirzepatide also demonstrated significant improvements in fasting insulin, blood pressure, lipid profiles, and overall glycaemic control, reinforcing its potential role in long-term metabolic health management

Additionally, choline is integral to fat and cholesterol metabolism, aiding in their breakdown

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