doi: 10.1016/j.appet.2022.106260 135
Accordingly, this strategy effectively reinstated TADC antigen-presenting function through a multi-tiered intervention targeting lipid uptake, synthesis, and transcription across extracellular, cytoplasmic, and nuclear compartments, thereby promoting CD8 + T-cell recruitment and activation
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This observation, coupled with the added stability contributed by C-terminal amidation and the desire to increase the hydrophobicity of the peptide, led to the generation of a series of compounds with the structure, N-acyl-Tyr-Ile-(6) amino -hexanoic amide
Cells were then harvested by centrifugation and washed with ice-cold 1 PBS