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Lilly is studying retatrutide in several Phase 3 clinical trials to evaluate its potential efficacy and safety in obesity and overweight with at least one weight-related medical problem, type 2 diabetes, knee osteoarthritis, moderate-to-severe obstructive sleep apnea, chronic low back pain, cardiovascular and renal outcomes, and metabolic dysfunction-associated steatotic liver disease

Everyone responds to semaglutide and berberine differently

Blood pressure should be assessed regularly, as both weight loss from tirzepatide and the antihypertensive effects of beta blockers may necessitate adjustments in blood pressure medications to avoid hypotension

This indicates that participants highly valued the treatment with oral semaglutide, even if their level of satisfaction was already good at baseline

Since GLP-1s can dull your thirst mechanism, you should aim for a specific daily fluid goal

In early 2025, the FDA ended the semaglutide shortage designation, which means compounding pharmacies no longer have the legal basis to produce copies of the drug