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In states of copper overload, interventions that remove excess copper or restore normal cellular copper transport have shown promise in improving cardiac and mitochondrial function in preclinical studies [51]

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BPC-157 supports this interconnected system by: Strengthening tight junctions between intestinal epithelial cells, reducing intestinal permeability (leaky gut) Modulating the enteric nervous system to normalize motility and reduce visceral hypersensitivity Regulating mucosal immune responses to prevent inappropriate inflammation against dietary and microbial antigens Conditions Treated with Oral BPC-157 Beyond Symptom Relief: Addressing Root Causes Unlike proton pump inhibitors (PPIs) that suppress stomach acid or corticosteroids that broadly dampen immunity, BPC-157 works by restoring the underlying structural and functional integrity of the gastrointestinal tract

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In that study, 68.4% of the VAX-D group achieved at least a 50% pain reduction, while none of the patients in the TENS group did (Naguszewski et al., 2001)