This effect does not seem to be a result of a whole-body metabolic shift, as these changes were not seen in adipose or skeletal muscle tissue
GLP-1 agonists alter transcriptional, proteomic, metabolic, immunologic, and neural dynamics in ways that cannot be captured by isolated measurements or siloed analytics
So you might be wondering: how do these medications work
Its also banned by the World Anti-Doping Agency (WADA) under its S0 classification meaning its considered a non-approved substance, prohibited at all times for athletes
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Similar findings were reported in two Cochrane database systematic reviews that analyzed the results from 15 trials involving over 20,000 women (91, 92)