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Exercising and eating a balanced diet - with correct portion sizing and adequate protein - is the best way to keep the weight off

Regulation of phosphoenolpyruvate carboxykinase (GTP) gene expression

Prefer ongoing in-person medical supervision and support: Some patients value the ability to meet regularly with a healthcare provider face-to-face to discuss progress, side effects, dosage adjustments, and challenges

This effect is particularly relevant in hypogonadal models and aging populations where GH-axis activity declines

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A broader metabolic reset, not just a weight intervention